AQC processes are of particular importance in laboratories analysing environmental samples where the concentration of chemical species present may be extremely low and close to the detection limit of the analytical method In well managed laboratories, AQC processes are built into the routine operations of the laboratory often by the random introduction of known standards into the sample stream or by the use of spiked samples
Quality control begins with sample collection and ends with the reporting of data ( S very important to be be noted dears AQC is achieved through laboratory control of analytical performance. Initial control of the complete system can be achieved through specification of laboratory ☄services,☄ instrumentation ☄glassware,☄ reagents,☄ solvents, and ☄gases. However, evaluation of daily performance must be documented to ensure continual production of valid data. A check should first be done to ensure that the data should be seen is precise and accurate. Next, systematic daily checks such as analysing ☄blanks, ☄calibration ☄standards, quality control check ☄samples, and references must be performed to establish the reproducibility of the data. The checks help certify that the methodology is measuring what is in the sample.
The quality of individual AQC efforts can be variable depending on the training, professional pride, and mportance of a particular project to a particular analyst. The burden of an individual analyst originating AQC efforts can be lessened through the implementation of quality assurance programs. Through the implementation of established and routine quality assurance programs, two primary functions are fulfilled: the determination of quality, and the control of confidence ( S -Really) By monitoring the accuracy and precision of results, the quality assurance program should increase confidence in the reliability of the reported analytical results, thereby achieving adequate AQC (Analytical quality control)
[As per experience AQA ? its framework to monitor for Quality in Quality control complete activities its should have defined SOP in the work r activities responsibilities Quality control generation all documents under custody Quality control for A to Z training Quality control generated all results should be checked should be before (FP/API) QA Quality control for incidence/deviations/OOS/CAPA/CC/ call respective should go to QA via AQA (then that original QA) If any results in electronic signature same checked by in quality control person ( Review) after results should confirm AQA Organogram/JD for arranging all persons ( QA/QC) etc.,
AQA – also should have trend for all like OOS/OOT/Incidence/Deviations/APQR (FP/API/RM/PM/CALIBRATION/TI SHEETS RESULTS etc.,
AQA- Quality control What are using any type of documents should be authorized by AQA /AQC r QA